PRODUCT CLASSIFICATION
GHRH Analogue
ACNE
None
WATER RETENTION
None
HBR
None
HEPATOTOXICITY
None
AROMATIZATION
None
MANUFACTURER
Beligas
WAREHOUSE
International Warehouse 3
ACTIVE SUBSTANCE
GHRH Peptide
Introducing CJC-1295, a powerful synthetic analogue of growth hormone-releasing hormone (GHRH) consisting of 30 amino acids. This innovative peptide is scientifically shown to significantly boost the secretion of growth hormone and IGF-1 while preserving the natural pulsatile release of GH.
Often used in synergy with Ipamorelin, CJC-1295 enhances specificity as a GHRH, promoting similar growth hormone increases without triggering appetite or elevating cortisol, acetylcholine, prolactin, and aldosterone levels typical of other peptides. Users consistently report excellent tolerance, making CJC-1295 a perfect companion for Ipamorelin.
Target Gland: Pituitary
Key Benefits of CJC-1295:
- Boosts growth hormone and IGF-1 levels without increasing prolactin
- Enhances body weight and lean muscle mass through improved protein synthesis
- Stimulates muscle development
- Increases bone density
- Supports immune function
- Enhances cognitive function and memory
- Stimulates collagen production for youthful skin
- Aids in fat reduction
- Facilitates cellular repair and regeneration
Why Choose CJC-1295? This remarkable peptide also promotes deep, restorative sleep, essential for optimizing muscle growth, improving memory, and achieving overall rejuvenation.
GHRH is naturally synthesized in the hypothalamus and stimulates the pituitary gland to release GH in a pulsatile manner. However, GHRH has a very short half-life of just a few minutes, leading to rapid elimination from the bloodstream and brief effects.
Types of CJC-1295: The active part of GHRH consists of the first 29 amino acids, available commercially as Sermorelin. This was further optimized to extend its half-life to 30 minutes, resulting in CJC-1295. Enhanced with a Drug Affinity Complex (DAC), CJC-1295 has a prolonged half-life of approximately 8 days, known as CJC-1295 + DAC. A non-DAC version is also available that mimics the natural nightly GH spike.
The extended half-life of CJC-1295 + DAC allows for injections just once or twice a week. However, this extended presence can lead to constant stimulation of GH release that may not mimic natural physiological patterns, potentially reducing GH pulse amplitude and leading to diminished effects on GH-responsive tissues.
For optimal use of long-acting CJC molecules, it is recommended to take "hormone holidays" every three to six months for three months at a time, allowing the pituitary gland to recover. During these breaks, Sermorelin serves as an ideal substitute for CJC-1295 + DAC.
Safety Considerations: These hormone holidays may also mitigate the risk of developing GH resistance, which can occur from the formation of antibodies against GH or a decrease in GH receptors on tissues (down-regulation). It is important to note that these concerns are theoretical, as extensive long-term studies have yet to be conducted.
Potential side effects of CJC-1295 may include injection site reactions (such as irritation, redness, swelling, pain, and itching), headaches, diarrhea, vasodilation (flushing, warmth, and transient low blood pressure), nausea, and abdominal discomfort.